Abstract
The traditional method of monitoring the oxidation and reduction of biomedical materials usually relies on electrochemical (EC) measurement techniques. Here, we demonstrate a surface plasmon resonance (SPR) method to monitor the oxidation process. Using levodopa L-dopa as the target analyte, a nanohole sensing plate is embedded in the EC electrode to enhance the oxidation signal and generate SPR. Cyclic voltammetry (CV) measurement was first conducted to understand the baseline of EC response of L-Dopa. Then, the redox reactions were simultaneously monitored through SPR measurements during the CV voltage scan. The results showed that the limit of detection using traditional CV reached 1.47 μM while using EC-SPR, the limit of detection improved to 1.23 μM. Most importantly, we found a strong correlation between CV current profiles and the SPR reflection spectra. Our results facilitate detecting electrochemical reactions using an optical probing method.
You have requested "on-the-fly" machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer
Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer
Details
1 Graduate Institute of Photonics and Optoelectronics, National Taiwan University, 10617, Taipei, Taiwan (ROR: https://ror.org/05bqach95) (GRID: grid.19188.39) (ISNI: 0000 0004 0546 0241)
2 Graduate Institute of Photonics and Optoelectronics, National Taiwan University, 10617, Taipei, Taiwan (ROR: https://ror.org/05bqach95) (GRID: grid.19188.39) (ISNI: 0000 0004 0546 0241); Department of Electrical Engineering, National Taiwan University, 10617, Taipei, Taiwan (ROR: https://ror.org/05bqach95) (GRID: grid.19188.39) (ISNI: 0000 0004 0546 0241)