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Abstract
The bactericidal properties of chemically patterned lithium niobate substrates under a super-bandgap UV light source is established. UV irradiation of lithium niobate surfaces inoculated with bacteria leads to antimicrobial activity compared to a glass substrate under similar conditions, as determined by surface enhanced Raman spectroscopy and corroborated with a fluorescence-based live/dead assay. This finding may expand the possible biomedical applications of lithium niobate.
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1 School of Physics, University College Dublin, Belfield, Dublin 4, Ireland; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin 4, Ireland
2 School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland; School of Veterinary Medicine, University of Kufa, Iraq
3 Laser and Optoelectronic Engineering Department, University of Technology -Iraq, Baghdad, Iraq; School of Chemistry, Trinity College Dublin, The University of Dublin, Dublin 4, Ireland
4 Department of Applied Physics, KTH – Royal Institute of Technology, Stockholm, Sweden
5 School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland
6 School of Physics, University College Dublin, Belfield, Dublin 4, Ireland