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Sakshi Sanjay Patil., Pallavi Arjun Patil., Rutuja. R. Shah
Anandi College of Pharmacy, Kalambe tarf Kale, Kolhapur.
* Corresponding Author E-mail: [email protected]
ABSTRACT:
Background: Emulgel is a topical preparation prepared by the mixture of an emulsion and a gel. Emulgel is considered as one of the most important topical delivery systems because it consists of two release control systems, i.e., a gel and an emulsion. The primary intention of this new topical delivery system is to deliver hydrophobic drugs into systemic circulation through the skin. By applying a suitable statistical design, different grades of emulgel can be prepared. There are various favorable properties. Therefore, emulgel is considered as the most conventional system available in the market over other topical drug delivery systems.
Objectives: In the present work an attempt was made to prepare emulgel of garlic oil and ajwain oil for enhancing its topical delivery. Material and Method: Emulgel formulation was characterized by various parameters like pH, viscosity, spredability, Extrudability, microbiological Assay.
KEYWORDS: Emulgel, Natural Drugs, Topical, Controlled Drug Delivery, Gelling agent.
INTRODUCTION:
DEFINATION:
Emulgels can be defined as it a new topical drug delivery method that can be created by mixing gel with water in emulsion and have benefits of both gels and emulsion1 Emulgel is a biphasic system comprising an apolar internal phase (emulsion) within an aqueous gel base.[2] Emulgel have a number of advantages over traditional semisolid dosage forms, emulgel have ability to deliver drugs in controlled manner.Emulgel is thixotropic, greaseless, easily spreadable, easily removable, emollient, and transparent in appearance.2 Emulgel are emulsions, either oil-in-water or water-in-oil type.3 In recent years, there has been great interest in use of novel polymers with complex function as emulsifiers and thickeners because the gelling capacity of these compounds allow the formulation of stable emulsion. The presence of gelling agent in water phase converts a classical emulsion into an emulgel.4
Regional delivery involves the application of drug to the skin for purpose of treating diseases or alleviating symptoms in deep tissue beneath the application5
Classification of Emulgel:
A)Based on the type of API
B)Based on the type of emulsion
A) Based on the type of API-
1) Herbal/Polyherbal:
e.g., i) Cosmetic emulgel for skin care from field pumpkin.
ii) Anti-psoriatic emulgel from babchi oil and Gum...