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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

The potential of Stropharia rugosoannulata as a microbial remediation material for cadmium (Cd)-contaminated soil lies in its capacity to absorb and accumulate Cd in its mycelia. This study utilized the TMT and LC−MS techniques to conduct integrated proteomic and metabolomic analyses with the aim of investigating the mycelial response mechanisms of S. rugosoannulata under low- and high-Cd stresses. The results revealed that mycelia employed a proactive defense mechanism to maintain their physiological functions, leading to reduced sensitivity to low-Cd stress. The ability of mycelia to withstand high levels of Cd stress was influenced primarily by the comprehensive regulation of six metabolic pathways, which led to a harmonious balance between nitrogen and carbohydrate metabolism and to reductions in oxidative stress and growth inhibition caused by Cd. The results provide valuable insights into the molecular mechanisms involved in the response of S. rugosoannulata mycelia to Cd stress.

Details

Title
Combined Proteomic and Metabolomic Analyses Reveal the Comprehensive Regulation of Stropharia rugosoannulata Mycelia Exposed to Cadmium Stress
Author
Qin Dong 1 ; Chen, Mingjie 1 ; Yu, Changxia 1 ; Zhang, Yaru 1 ; Zha, Lei 1 ; Kakumyan, Pattana 2   VIAFID ORCID Logo  ; Yang, Huanling 1 ; Zhao, Yan 1   VIAFID ORCID Logo 

 Institute of Edible Fungi, Shanghai Academy of Agricultural Sciences, Shanghai 201403, China; [email protected] (Q.D.); [email protected] (M.C.); [email protected] (C.Y.); [email protected] (Y.Z.); [email protected] (L.Z.); [email protected] (H.Y.) 
 School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand; [email protected] 
First page
134
Publication year
2024
Publication date
2024
Publisher
MDPI AG
e-ISSN
2309608X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
2930956521
Copyright
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.