Caracterisation et simulation de la migration des sources dans le traitement par implants permanents transperineaux du cancer de la prostate
Abstract (summary)
Le traitement du carcinome de la prostate par implantation transperineale permanente de sources radioactives connai t une popularite grandissante en Amerique du nord. La migration des sources est le nom donne a l'ensemble des phenomenes causant une erreur de positionnement des sources radioactives, pendant ou apres l'implantation. La caracterisation de la migration etablit que la cause principale de mauvais positionnement est un deplacement longitudinal cause par la friction entre les tissus et l'aiguille utilisee pour l'insertion. Ce deplacement degrade la qualite de l'implant. L'indice de qualite "dose volume histogram" passe de plus de 99% en previsionnel a 82% en post-implant. Un programme de simulation par ordinateur est developpe a partir de la caracterisation. Le programme genere de facon aleatoire un ensemble d'implants simules sur lesquels sont mesures les indices de qualite. L'utilisation du programme permet d'ameliorer la technique en la rendant moins sensible a la migration.
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The treatment of prostate carcinoma by permanent transperineal implantation of radioactive sources is growing in popularity in North America. Source migration is the name given to all the phenomena causing an error in the positioning of radioactive sources, during or after implantation. Characterization of migration establishes that the main cause of poor positioning is longitudinal displacement caused by friction between the tissues and the needle used for insertion. This movement degrades the quality of the implant. The “dose volume histogram” quality index goes from more than 99% forecast to 82% post-implantation. A computer simulation program is developed from the characterization. The program randomly generates a set of simulated implants on which the quality indices are measured. Using the program allows you to improve the technique by making it less sensitive to migration.
Indexing (details)
Radiology;
Oncology;
Biomedical research;
Biomedical engineering;
Medical imaging
0992: Oncology
0541: Biomedical engineering
0786: Biophysics