Evaluation clinique d'une nouvelle modalité de traitement avec guidage en temps réel par imagerie

Abstract

Lors du traitement du cancer de la prostate en radiothérapie externe, la non reproductibilité du positionnement du patient à chaque traitement, causée entre autre par la présence du mouvement interne des organes, a apporté la venue d'une nouvelle technique de traitement. Cette nouvelle méthode consiste à implanter trois grains d'or dans la prostate avant le traitement. Ces grains jouent le rôle de marqueurs radio-opaques et permettent de situer la prostate et d'évaluer son déplacement par rapport aux faisceaux d'irradiation, donnant la possibilité de corriger ces déviations en temps réel. Ces corrections sont faites avec l'utilisation d'un système d'imagerie portale électronique standard. Le but de l'étude fut d'évaluer la possibilité de l'intégration clinique d'un algorithme de détection automatique de marqueurs radio-opaques, permettant d'obtenir de façon directe les corrections nécessaires pour le bon positionnement du patient lors de l'irradiation. L'impact dosimétrique de ces déplacements a aussi été évalué par simulation.

Alternate abstract:

You are viewing a machine translation of selected content from our databases. This functionality is provided solely for your convenience and is in no way intended to replace human translation. Show full disclaimer

Neither ProQuest nor its licensors make any representations or warranties with respect to the translations. The translations are automatically generated "AS IS" and "AS AVAILABLE" and are not retained in our systems. PROQUEST AND ITS LICENSORS SPECIFICALLY DISCLAIM ANY AND ALL EXPRESS OR IMPLIED WARRANTIES, INCLUDING WITHOUT LIMITATION, ANY WARRANTIES FOR AVAILABILITY, ACCURACY, TIMELINESS, COMPLETENESS, NON-INFRINGMENT, MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. Your use of the translations is subject to all use restrictions contained in your Electronic Products License Agreement and by using the translation functionality you agree to forgo any and all claims against ProQuest or its licensors for your use of the translation functionality and any output derived there from. Hide full disclaimer

During the treatment of prostate cancer by external radiotherapy, the non-reproducibility of the positioning of the patient at each treatment, caused among other things by the presence of the internal movement of the organs, brought the arrival of a new treatment technique. This new method consists of implanting three gold grains in the prostate before treatment. These grains play the role of radio-opaque markers and make it possible to locate the prostate and to evaluate its displacement in relation to the irradiation beams, giving the possibility of correcting these deviations in real time. These corrections are made with the use of a standard electronic portal imaging system. The purpose of the study was to evaluate the possibility of clinical integration of an algorithm for the automatic detection of radiopaque markers, making it possible to directly obtain the corrections necessary for the correct positioning of the patient during irradiation. The dosimetric impact of these movements was also evaluated by simulation.