Abstract

Background

The Ryan White Medical Case Management System, which serves more than half of people living with HIV (PLWH) in the USA, is an opportune setting for identifying and addressing depression among PLWH. A growing body of research suggests that interventions that promote positive emotion may lessen symptoms of depression and improve physical and psychological well-being among people experiencing a variety of health-related stress, including living with HIV. Research on how best to integrate standardized mental health screening and referral to evidence-based interventions in Ryan White Medical Case Management settings has the potential to improve the health and wellbeing of PLWH.

Methods

This mixed-methods study will enroll up to N = 300 Ryan White clients who screen positive for depressive symptoms in ORCHID (Optimizing Resilience and Coping with HIV through Internet Delivery), a web-based, self-guided positive emotion regulation intervention. The study will be conducted in 16 Ryan White Medical Case Management clinics in Chicago, IL. Following pre-implementation surveys and interviews with Medical Case Managers (MCMs) and Supervisors to develop an implementation facilitation strategy, we will conduct a hybrid type 2 implementation-effectiveness stepped wedge cluster randomized trial to iteratively improve the screening and referral process via interviews with MCMs in each wedge. We will test the effectiveness of ORCHID on depression and HIV care outcomes for PLWH enrolled in the program. RE-AIM is the implementation outcomes framework and the Consolidated Framework for Implementation Research is the implementation determinants framework.

Discussion

Study findings have the potential to improve mental health and substance use screening of Ryan White clients, decrease depression and improve HIV care outcomes, and inform the implementation of other evidence-based interventions in the Ryan White Medical Case Management System.

Trial registration

ClinicalTrials.gov NCT05123144. Trial registered 6/24/2021

Details

Title
A hybrid type II effectiveness-implementation trial of a positive emotion regulation intervention among people living with HIV engaged in Ryan White Medical Case Management: protocol and design for the ORCHID study
Author
Xavier Hall, Casey D. 1 ; Ethier, Kristen 2 ; Cummings, Peter 3 ; Freeman, Angela 4 ; Bovbjerg, Katrin 3 ; Bannon, Jacqueline 3 ; Dakin, Andrea 5 ; Abujado, Fay 5 ; Bouacha, Nora 5 ; Derricotte, Devan 5 ; Patterson, Lakethia 5 ; Hirschhorn, Lisa R. 3 ; Bouris, Alida 6 ; Moskowitz, Judith T. 3   VIAFID ORCID Logo 

1  Florida State University, Center of Population Science for Health Equity, College of Nursing, Tallahassee, USA (GRID:grid.255986.5) (ISNI:0000 0004 0472 0419); Florida State University, School of Social Work, Tallahassee, USA (GRID:grid.255986.5) (ISNI:0000 0004 0472 0419); Northwestern University Feinberg School of Medicine, Department of Medical Social Sciences, Chicago, USA (GRID:grid.16753.36) (ISNI:0000 0001 2299 3507) 
2  Simmons University, School of Social Work, Boston, USA (GRID:grid.28203.3b) (ISNI:0000 0004 0378 6053) 
3  Northwestern University Feinberg School of Medicine, Department of Medical Social Sciences, Chicago, USA (GRID:grid.16753.36) (ISNI:0000 0001 2299 3507) 
4  Northwestern University Feinberg School of Medicine, Department of Medical Social Sciences, Chicago, USA (GRID:grid.16753.36) (ISNI:0000 0001 2299 3507); AIDS Foundation Chicago, Chicago, USA (GRID:grid.16753.36) 
5  AIDS Foundation Chicago, Chicago, USA (GRID:grid.16753.36) 
6  University of Chicago, Crown Family School of Social Work, Policy, and Practice, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822); University of Chicago, Chicago Center for HIV Elimination, Chicago, USA (GRID:grid.170205.1) (ISNI:0000 0004 1936 7822) 
Pages
631
Publication year
2024
Publication date
Dec 2024
Publisher
Springer Nature B.V.
e-ISSN
17456215
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/s13063-024-08475-1
ProQuest document ID
3110549136
Copyright
© The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.