Abstract

The role of genomic research and medicine in improving health continues to grow significantly, highlighting the need for increased equitable inclusion of diverse populations in genomics. Native Hawaiian and Pacific Islander (NHPI) communities are often missing from these efforts to ensure that the benefits of genomics are accessible to all individuals. In this article, we analyze the qualities of NHPI populations relevant to their inclusion in genomic research and investigate their current representation using data from the genome-wide association studies (GWAS) catalog. A discussion of the barriers NHPI experience regarding participating in research and recommendations to improve NHPI representation in genomic research are also included.

Details

Title
Native Hawaiian and Pacific Islander populations in genomic research
Author
Ha, Edra K. 1   VIAFID ORCID Logo  ; Shriner, Daniel 2   VIAFID ORCID Logo  ; Callier, Shawneequa L. 3   VIAFID ORCID Logo  ; Riley, Lorinda 4 ; Adeyemo, Adebowale A. 2   VIAFID ORCID Logo  ; Rotimi, Charles N. 2   VIAFID ORCID Logo  ; Bentley, Amy R. 2   VIAFID ORCID Logo 

1  National Institutes of Health, Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165); University of Hawaiʻi at Mānoa, Honolulu, USA (GRID:grid.410445.0) (ISNI:0000 0001 2188 0957); University of Pittsburgh School of Medicine, Pittsburgh, USA (GRID:grid.21925.3d) (ISNI:0000 0004 1936 9000) 
2  National Institutes of Health, Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165) 
3  National Institutes of Health, Center for Research on Genomics and Global Health, National Human Genome Research Institute, Bethesda, USA (GRID:grid.94365.3d) (ISNI:0000 0001 2297 5165); The George Washington University School of Medicine and Health Sciences, Department of Clinical Research and Leadership, Washington, USA (GRID:grid.253615.6) (ISNI:0000 0004 1936 9510) 
4  University of Hawaiʻi at Mānoa, Honolulu, USA (GRID:grid.410445.0) (ISNI:0000 0001 2188 0957) 
Pages
45
Publication year
2024
Publication date
2024
Publisher
Nature Publishing Group
e-ISSN
20567944
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1038/s41525-024-00428-6
ProQuest document ID
3111349488
Copyright
© This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.