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© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.

Abstract

Simple Summary

Staphylococcus pseudintermedius (SP) is a commensal and opportunistic pathogen of canine skin and mucosal surfaces that rapidly gained attention due to its increasing antibiotic resistance. Platelet-rich plasma (PRP) is an autologous biological product, which has antibacterial properties, obtained from blood using a centrifugation process. The aim of this study was evaluating the antimicrobial effect of canine leucocyte-rich PRP (L-PRP) and platelet-poor plasma (PPP) against two field strains of SP isolated from dogs affected by pyoderma: one MDR strain and one non-MDR strain, using the micro-inhibition in broth method. L-PRP and PPP had a similar significant antimicrobial effect against both non-MDR and MDR SP strains. More studies are necessary to confirm these results, considering the rise in MDR and pan-drug-resistant bacteria.

Details

Title
Antibacterial Effect of Canine Leucocyte Platelet-Rich Plasma (L-PRP) and Canine Platelet-Poor Plasma (PPP) Against Methicillin-Sensitive and Methicillin-Resistant Staphylococcus pseudintermedius
Author
Perego, Roberta 1   VIAFID ORCID Logo  ; Meroni, Gabriele 2   VIAFID ORCID Logo  ; Martino, Piera Anna 2   VIAFID ORCID Logo  ; Spada, Eva 1   VIAFID ORCID Logo  ; Baggiani, Luciana 1 ; Proverbio, Daniela 1   VIAFID ORCID Logo 

 Veterinary Transfusion Research Laboratory (REVLab), Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell’Università 6, 26900 Lodi, Italy; [email protected] (E.S.); [email protected] (L.B.); [email protected] (D.P.) 
 One Health Unit, Department of Biomedical, Surgical, and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milan, Italy; [email protected] 
First page
670
Publication year
2024
Publication date
2024
Publisher
MDPI AG
e-ISSN
23067381
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3149763120
Copyright
© 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.