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Abstract
Lower respiratory tract infections (LRTIs) in pediatric patients, encompassing entities such as bronchiolitis and pneumonia, present a multifaceted clinical challenge. This study delves into the complexity of pediatric LRTIs, considering diverse pathogens, clinical manifestations, and the influence of viral epidemics. Epidemiological insights reveal a global impact, with a notable burden on mortality and morbidity, particularly in the first years of life.
The retrospective cohort study, conducted at a Children's Emergency Clinical Hospital, explores the clinical and paraclinical profile of 145 pediatric patients diagnosed with LRTIs between January 2022 and December 2022. Descriptive statistics of hospitalization days, C-reactive protein (CRP), and procalcitonin (PCT) values provide insights into the clinical-paraclinical dynamics.
Respiratory failure primarily results from viral infections, showcasing the need for targeted interventions. The study identifies Staphylococcus aureus and respiratory syncytial virus as prevalent etiological agents. Notably, antibiotic therapy, primarily cephalosporins, is employed in 86.2% of cases.
This comprehensive analysis contributes to a nuanced understanding of pediatric LRTIs, guiding personalized treatment strategies and preventive measures. The study serves as a valuable resource for clinicians and researchers, fostering advancements in pediatric respiratory care.
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Details
1 Pediatric Departament. Clinical Emergency Hospital for Children "Sfântul Ioan", Galați, Romania
2 Pediatric Departament. Clinical Emergency Hospital for Children "Sfântul Ioan", Galați, Romania; Clinical Medical Department, ”Dunărea de Jos” University, Faculty of Medicine and Pharmacy, Galati, Romania
3 ICU Departament, County Emergency Clinical Hospital Sfântul Apostol Andrei, Galati, Romania
4 Department of Morphological and Functional Sciences, Dunărea de Jos” University, Faculty of Medicine and Pharmacy, Galati, Romania
5 Medical Department, ”Dunărea de Jos” University, Faculty of Medicine and Pharmacy, Galati, Romania