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Abstract

Background: This study presents a comprehensive analysis of 135 cases of vestibular schwannoma (VS) treated between 2006 and 2022 at the National Institute of Neurology and Neurovascular Diseases in Bucharest, Romania. The investigation focuses on the clinical presentation, treatment outcomes, and demographic trends of VS patients, highlighting region-specific insights that fill critical gaps in Eastern European data. Methods: Patients were treated with either open surgery (93.3%) or gamma knife radiosurgery (6.6%). The study identifies predominant symptoms, including hearing impairment, facial palsy, and balance disorders, with variations observed across age and gender subgroups. Comorbidities such as hypertension and obesity were prevalent, and they influenced perioperative risks. Results: Post-treatment outcomes showed a significant correlation between clinical symptoms and treatment modalities, with a majority achieving favorable results. The findings emphasize the need for tailored approaches in VS management and underscore the importance of region-specific factors in influencing clinical outcomes. Conclusions: This study contributes to refining treatment strategies and improving healthcare delivery for VS patients in Romania and beyond.

Details

1009240
Company / organization
Title
Clinical Presentation, Treatment Outcomes, and Demographic Trends in Vestibular Schwannomas: A 135-Case Retrospective Study
Author
Toader, Corneliu 1 ; Rădoi, Petrinel Mugurel 1   VIAFID ORCID Logo  ; Milena-Monica Ilie 2 ; Razvan-Adrian Covache-Busuioc 1 ; Buica, Vlad 2 ; Luca-Andrei Glavan 2 ; Serban, Matei 1 ; Corlatescu, Antonio Daniel 2   VIAFID ORCID Logo  ; Crivoi, Carla 3 ; Radu Mircea Gorgan 4 

 Department of Neurosurgery, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania; [email protected] (C.T.); [email protected] (M.-M.I.); [email protected] (R.-A.C.-B.); [email protected] (V.B.); [email protected] (L.-A.G.); [email protected] (M.S.); [email protected] (A.D.C.); [email protected] (R.M.G.); Department of Vascular Neurosurgery, National Institute of Neurology and Neurovascular Diseases, 077160 Bucharest, Romania 
 Department of Neurosurgery, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania; [email protected] (C.T.); [email protected] (M.-M.I.); [email protected] (R.-A.C.-B.); [email protected] (V.B.); [email protected] (L.-A.G.); [email protected] (M.S.); [email protected] (A.D.C.); [email protected] (R.M.G.) 
 Faculty of Mathematics and Computer Science, University of Bucharest, 050663 Bucharest, Romania; [email protected] 
 Department of Neurosurgery, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania; [email protected] (C.T.); [email protected] (M.-M.I.); [email protected] (R.-A.C.-B.); [email protected] (V.B.); [email protected] (L.-A.G.); [email protected] (M.S.); [email protected] (A.D.C.); [email protected] (R.M.G.); Department of Neurosurgery, Bagdasar-Arseni Clinical Emergency Hospital, 041915 Bucharest, Romania 
Publication title
Volume
14
Issue
2
First page
482
Publication year
2025
Publication date
2025
Publisher
MDPI AG
Place of publication
Basel
Country of publication
Switzerland
Publication subject
e-ISSN
20770383
Source type
Scholarly Journal
Language of publication
English
Document type
Journal Article
Publication history
 
 
Online publication date
2025-01-14
Milestone dates
2024-07-26 (Received); 2025-01-09 (Accepted)
Publication history
 
 
   First posting date
14 Jan 2025
ProQuest document ID
3159460603
Document URL
https://www.proquest.com/scholarly-journals/clinical-presentation-treatment-outcomes/docview/3159460603/se-2?accountid=208611
Copyright
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2025-01-24
Database
2 databases
  • Coronavirus Research Database
  • ProQuest One Academic