In Table 1, there are errors in the values indicated to the columns of p16 immunostaining of rows “Non-invasive papillary urothelial carcinoma, pTa G2 low grade”, “Non-invasive papillary urothelial carcinoma, pTa G2 high grade” and “Non-invasive papillary urothelial carcinoma, pTa G3” under the category of Tumors of the urinary system. Also, the “(neg. = negative, mod. = moderate, pos. = positive).” is missing from its caption. Please see the correct Table 1 and its complete caption here.
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Table 1. p16 immunostaining in human tumors (neg. = negative, mod. = moderate, pos. = positive).
https://doi.org/10.1371/journal.pone.0318271.t001
In the S2 Table, the values in the rows “Non-invasive papillary urothelial carcinoma, pTa G2 low grade”, “Non-invasive papillary urothelial carcinoma, pTa G2 high grade” and Non-invasive papillary urothelial carcinoma, pTa G3 of the organ urinary system are incorrect. The authors have provided the correct version of S2 Table here.
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S2 Table. p16 positive and p16 negative normal tissues and associated tumor types.
https://doi.org/10.1371/journal.pone.0318271.t002
In Figs 3 and 4, the ranking order of tumor types is incorrect. Please see the correct Figs 3 and 4 here.
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Fig 3. Ranking order of p16 immunostaining in human tumors.
Both the frequency of positive cases (blue dots) and the frequency of strongly positive cases (orange dots) is shown.
https://doi.org/10.1371/journal.pone.0318271.g001
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Fig 5. Graphical representation of p16 data from this study (marked with a cross) in comparison with data from existing literature (marked with dots).
In order to simplify the figure the percentage of weak, moderate and strong staining was merged. Red dots are used for previous studies involving 1–9 cases, yellow dots for studies involving 10–50 cases and green dots for studies involving >50 cases. All studies are quoted in a list of references in S1 Table.
https://doi.org/10.1371/journal.pone.0318271.g002
There is an error in fourth sentence of the Abstract section. The correct sentence is: In cancer, highest positivity rates were observed in uterine cervix squamous cell carcinomas (94.4%), Merkel cell carcinoma (97.7%), and small cell carcinomas of various sites of origin (54.5%-100%).
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