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Abstract
In order to quantify radiation risks at exposure scenarios relevant for radiation protection, often extrapolation of data obtained at high doses and high dose rates down to low doses and low dose rates is needed. Task Group TG91 on ‘Radiation Risk Inference at Low-dose and Low-dose Rate Exposure for Radiological Protection Purposes’ of the International Commission on Radiological Protection is currently reviewing the relevant cellular, animal and human studies that could be used for that purpose. This paper provides an overview of dose rates and doses typically used or present in those studies, and compares them with doses and dose rates typical of those received by the A-bomb survivors in Japan.
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1 Institute of Radiation Protection, Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany
2 Southern Urals Biophysics Institute (SUBI), Ozyorskoe Shosse 19, 456780, Ozyorsk, Chelyabinsk Region, Russian Federation
3 Centre for Radiation, Chemical and Environmental Hazards, Public Health England (PHE), Chilton, Didcot OX11 ORQ, UK
4 Radiation Effects Research Foundation, 5–2 Hijiyama Park, Minami-ku, Hiroshima 732-0815, Japan
5 Federal Office for Radiation Protection, Ingolstädter Landstr. 1, 85764 Oberschleißheim, Germany
6 Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Drive, Bethesda, MD 20892-9778, USA
7 New York University School of Medicine, 650 First Ave., New York, NY 10016, USA
8 Medical Physics Group, Department of Physics, Science Faculty, University of Zürich, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland
9 Departments of Radiation Oncology, Radiology, and Cell and Molecular Biology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, 300 E. Superior St., Tarry 4-760, Chicago, IL 60611, USA