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Abstract
Treatment of cryptococcosis requires deferred initiation of antiretroviral therapy (ART). Early ART initiation may be detrimental in the context of cryptococcal infection by increasing the risk of immune reconstitution inflammatory syndrome (IRIS). We present 3 cases where early ART initiation in the presence of unrecognized cryptococcal disease had fatal outcomes.
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Details
1 Infectious Diseases Institute, Kampala, Uganda; University of Minnesota, Minneapolis, Minnesota
2 Infectious Diseases Institute, Kampala, Uganda; University of Minnesota, Minneapolis, Minnesota; School of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda
3 University of Minnesota, Minneapolis, Minnesota