Abstract

In the Swiss HIV Cohort Study, the number of people who inject drugs with replicating hepatitis C virus (HCV) infection decreased substantially after the introduction of direct-acting antivirals (DAAs). Among men who have sex with men, the increase in DAA uptake and efficacy was counterbalanced by frequent incident HCV infections.

Details

Title
Impact of Direct-Acting Antivirals on the Burden of HCV Infection Among Persons Who Inject Drugs and Men Who Have Sex With Men in the Swiss HIV Cohort Study
Author
Salazar-Vizcaya, Luisa 1 ; Wandeler, Gilles 2 ; Fehr, Jan 3 ; Braun, Dominique 4 ; Cavassini, Matthias 5 ; Stoeckle, Marcel 6 ; Bernasconi, Enos 7 ; Hoffmann, Matthias 8 ; Rougemont, Mathieu 9 ; Béguelin, Charles 1 ; Rauch, Andri 1 ; Aubert, V; Battegay, M; Bernasconi, E; Böni, J; Braun, D L; Bucher, H C; Calmy, A; Cavassini, M; Ciuffi, A; Dollenmaier, G; Egger, M; Elzi, L; Fehr, J; Fellay, J; Furrer, H; Fux, C A; Günthard, H F; Haerry, D; Hasse, B; Hirsch, H H; Hoffmann, M; Hösli, I; Kahlert, C; Kaiser, L; Keiser, O; Klimkait, T; Kouyos, R D; Kovari, H; Ledergerber, B; Martinetti, G; Martinez de Tejada, B; Marzolini, C; Metzner, K J; Müller, N; Nicca, D; Pantaleo, G; Paioni, P; Rauch, A; Rudin, C; Scherrer, A U; Schmid, P; Speck, R; Stöckle, M; Tarr, P; Trkola, A; Vernazza, P; Wandeler, G; Weber, R; Yerly, S

1  Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland 
2  Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland; Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland 
3  Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Department of Public Health, Epidemiology, Biostatistic and Prevention Institute, University of Zurich, Zurich, Switzerland 
4  Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland; Institute of Medical Virology, University of Zurich, Zurich, Switzerland; Division of Infectious Diseases, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland 
5  Institute of Medical Virology, University of Zurich, Zurich, Switzerland; Division of Infectious Diseases, University Hospital Lausanne, University of Lausanne, Lausanne, Switzerland 
6  Department of Infectious Diseases and Hospital Hygiene, University Hospital Basel, Basel, Switzerland 
7  Division of Infectious Diseases, Regional Hospital Lugano, Lugano, Switzerland 
8  Division of Infectious Diseases and Hospital Epidemiology, Cantonal Hospital St. Gallen, St. Gallen, Switzerland 
9  Division of Infectious Diseases, University Hospital Geneva, University of Geneva, Geneva, Switzerland 
Publication year
2018
Publication date
Jul 2018
Publisher
Oxford University Press
e-ISSN
23288957
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1093/ofid/ofy154
ProQuest document ID
3170955943
Copyright
© The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.