Abstract

Background

Evaluating the National Institute’s Health’s (NIH's) response to the coronavirus disease 2019 (COVID-19) pandemic via grants and clinical trials is crucial to determining the impact they had on aiding US citizens. We determined how the NIH's funding for COVID-19 research was disbursed and used by various institutions across the United States.

Methods

We queried NIH RePORTER and isolated COVID-19–related grants from January 2020 to December 2021. We analyzed grant type, geographical location, and awardee institution. Manuscripts published from these grants were quantitatively analyzed. COVID-19 clinical trials were mapped and distances from counties to clinical trial sites were calculated using ArcGis.

Results

A total of 2401 COVID-19 NIH grants resulted in 14 654 manuscripts from $4.2 billion and generated more than 150 000 citations. R01s make up 32% of grants (763/2401) and 8% of funding ($329 million). UM1 grants account for the majority of funding (30.8%; $1.3 Billion). Five states received 50.6% of funding: North Carolina, Washington, New York, California, and Massachusetts. Finally, of the 1806 clinical trials across 1266 sites in the United States, the majority were in metropolitan areas in close proximity to areas of high COVID-19 disease burden.

Conclusions and Relevance

Evaluating the outcome of the NIH's response to the COVID-19 pandemic is of interest to the general public. The present study finds that the NIH disbursed more than $4 billion in funding to large consortiums and clinical trials to develop diagnostics, therapeutics, and vaccines. Approximately 8% of funding was used for R01 grants. Clinical trial sites were generally located in areas of high COVID-19 burden.

Details

Title
Analysis of National Institutes of Health Funding for the COVID-19 Pandemic
Author
Narahari, Adishesh K 1 ; Horgan, Taylor M 2 ; Chandrabhatla, Anirudha S 2 ; Gist, D Chris 2 ; Patel, Paranjay D 3 ; Lantieri, Mark A 4 ; Sturek, Jeffrey M 2 ; Davis, Claire L 2 ; Jackson, Patrick E H 2 ; Bell, Taison D 2 

 Division of Cardiothoracic Surgery, University of Virginia School of Medicine , Charlottesville, Virginia , USA 
 School of Medicine, University of Virginia , Charlottesville, Virginia, USA 
 Department of Cardiovascular Surgery, Houston Methodist Hospital , Houston, Texas , USA 
 Department of Orthopedic Surgery, Johns Hopkins Hospital , Baltimore, Maryland , USA 
Publication year
2024
Publication date
Mar 2024
Publisher
Oxford University Press
e-ISSN
23288957
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
3170974836
Copyright
© The Author(s) 2024. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This work is published under https://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.