Abstract

Lay Summary: Competition often occurs among diverse parasites within a single host, but control efforts could change its strength. We examined how the interplay between competition and control could shape the evolution of parasite traits like drug resistance and disease severity.

Details

Title
Evolutionary consequences of feedbacks between within-host competition and disease control
Author
Greischar, Megan A 1 ; Alexander, Helen K 2 ; Bashey, Farrah 3 ; Bento, Ana I 4 ; Bhattacharya, Amrita 3 ; Bushman, Mary 5 ; Childs, Lauren M 6 ; Daversa, David R 7 ; Day, Troy 8 ; Faust, Christina L 9 ; Gallagher, Molly E 5 ; Gandon, Sylvain 10 ; Glidden, Caroline K 11 ; Halliday, Fletcher W 12 ; Hanley, Kathryn A 13 ; Kamiya, Tsukushi 1 ; Read, Andrew F 14 ; Schwabl, Philipp 9 ; Sweeny, Amy R 2 ; Tate, Ann T 15 ; Thompson, Robin N 16 ; Wale, Nina 17 ; Wearing, Helen J 18 ; Yeh, Pamela J 19 ; Mideo, Nicole 1 

1  Department of Ecology & Evolutionary Biology, University of Toronto, 25 Willcocks St., Toronto, ON M5S 3B2, Canada 
2  Department of Zoology, University of Oxford, Zoology Research and Administration Building, 11a Mansfield Road, Oxford OX1 3SZ, UK 
3  Department of Biology, Indiana University, 1001 E. 3rd St., Bloomington, IN 47405, USA 
4  Odum School of Ecology and the Center for the Ecology of Infectious Diseases, University of Georgia, 140 E Green St., Athens, GA 30602, USA 
5  Department of Biology, Emory University, Atlanta, GA 30322, USA 
6  Department of Mathematics, McBryde Hall, Virginia Tech, Blacksburg, VA 24061, USA 
7  Institute of Integrative Biology, University of Liverpool, Liverpool, L69 3BX, UK; Institute of Zoology, Zoological Society of London, Regent’s Park, NW1 4RY, UK 
8  Departments of Mathematics & Biology, Jeffery Hall, Queen’s University, Kingston, ON K7L 3N6, Canada 
9  Institute of Biodiversity, Animal Health & Comparative Medicine, University of Glasgow, Glasgow G12 8QQ, UK 
10  CEFE UMR 5175, CNRS - Université de Montpellier, Université Paul-Valéry Montpellier, EPHE, 1919, Route de Mende, 34293 Montpellier Cedex 5, France 
11  Department of Integrative Biology, Oregon State University, 3029 Cordley Hall Corvallis, OR 97331, USA 
12  Department of Evolutionary Biology and Environmental Studies, University of Zürich, Zürich, 8057, Switzerland 
13  Department of Biology, New Mexico State University, Foster Hall, Las Cruces, NM 88003, USA 
14  Center for Infectious Disease Dynamics, Huck Institutes for the Life Sciences; Departments of Biology and Entomology, Pennsylvania State University, University Park, PA 16802, USA 
15  Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA 
16  Department of Zoology, University of Oxford, Zoology Research and Administration Building, 11a Mansfield Road, Oxford OX1 3SZ, UK; Mathematical Institute, University of Oxford, Woodstock Road, Oxford OX2 6GG, UK; Christ Church, University of Oxford, St Aldates, Oxford OX1 1DP, UK 
17  Department of Ecology & Evolutionary Biology, University of Michigan, 1105 North University Ave, Biological Sciences Building, Ann Arbor, MI 48109, USA 
18  Departments of Biology and Mathematics & Statistics, The University of New Mexico, Albuquerque, NM 87131, USA 
19  Department of Ecology & Evolutionary Biology, University of California, Los Angeles, 621 Charles E Young Dr South, Los Angeles, CA 90095, USA 
Pages
30-34
Publication year
2020
Publication date
2020
Publisher
Oxford University Press
e-ISSN
20506201
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1093/emph/eoaa004
ProQuest document ID
3171848178
Copyright
© The Author(s) 2020. Published by Oxford University Press on behalf of the Foundation for Evolution, Medicine, and Public Health. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.