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Abstract
Aim. To study the ability of pyocins to prevent biofilm formation of P. aeruginosa. Conclusions. A single preventive application of pyocins with 20.5-51.2x103 AU/mL activity affects P. aeruginosa UCM B-3 and UCM B-10 biofilm formation. It prevents the reproduction of microorganisms in planktonic (up to 14500 times) and biofilm (up to 92 times) forms and also slows down the biofilm formation (up to 53%) within 24-48 hours.