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Abstract

The field of bio-nanotechnology has seen significant advancements in recent years, particularly in the synthesis and application of bio-nanoparticles (BNPs). This review focuses on the green synthesis of BNPs using biological entities such as plants, bacteria, fungi, and algae. The utilization of these organisms for nanoparticle synthesis offers an eco-friendly and sustainable alternative to conventional chemical and physical methods, which often involve toxic reagents and high energy consumption. Phytochemicals present in plant extracts, unique metabolic pathways, and biomolecules in bacteria and fungi, and the rich biochemical composition of algae facilitate the production of nanoparticles with diverse shapes and sizes. This review further explores the wide-ranging applications of BNPs in various fields like therapeutics, fuel cells, energy generation, and wastewater treatment. In therapeutics, BNPs have shown efficacy in antimicrobial, anti-inflammatory, antioxidant, and anticancer activities. In the energy sector, BNPs are being integrated into fuel cells and other energy generation systems like bio-diesel to improve efficiency and sustainability. Their catalytic properties and large surface area enhance the performance of these devices. Wastewater treatment is another critical area where BNPs are employed for the removal of heavy metals, organic pollutants, and microbial contaminants, offering a cost-effective and environmentally friendly solution to water purification. This comprehensive review highlights the potential of bio-nanoparticles synthesized through green methods. It highlights the need for further research to optimize synthesis processes, understand mechanisms of action, and expand the scope of their applications. BNPs can be utilized to address advantages and some of the pressing challenges in medicine, energy, and environmental sustainability, paving the way for innovative and sustainable technological advancements in future prospects.

Details

1009240
Business indexing term
Title
Advancements in Bio-Nanotechnology: Green Synthesis and Emerging Applications of Bio-Nanoparticles
Author
M D K M Gunasena 1   VIAFID ORCID Logo  ; G D C P Galpaya 2 ; Abeygunawardena, C J 3 ; Induranga, D K A 4   VIAFID ORCID Logo  ; Priyadarshana, H V V 4   VIAFID ORCID Logo  ; Millavithanachchi, S S 5 ; P K G S S Bandara 5   VIAFID ORCID Logo  ; Koswattage, K R 4   VIAFID ORCID Logo 

 Department of Biosystems Technology, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka; [email protected] (M.D.K.M.G.); [email protected] (S.S.M.); [email protected] (P.K.G.S.S.B.); Center for Nanodevice Fabrication and Characterization, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka; [email protected] (G.D.C.P.G.); [email protected] (D.K.A.I.); [email protected] (H.V.V.P.) 
 Center for Nanodevice Fabrication and Characterization, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka; [email protected] (G.D.C.P.G.); [email protected] (D.K.A.I.); [email protected] (H.V.V.P.) 
 Department of Chemistry and Biochemistry, Baylor University, Waco, TX 76706, USA; [email protected] 
 Center for Nanodevice Fabrication and Characterization, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka; [email protected] (G.D.C.P.G.); [email protected] (D.K.A.I.); [email protected] (H.V.V.P.); Department of Engineering Technology, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka 
 Department of Biosystems Technology, Faculty of Technology, Sabaragamuwa University of Sri Lanka, Belihuloya 70140, Sri Lanka; [email protected] (M.D.K.M.G.); [email protected] (S.S.M.); [email protected] (P.K.G.S.S.B.) 
Publication title
Volume
15
Issue
7
First page
528
Publication year
2025
Publication date
2025
Publisher
MDPI AG
Place of publication
Basel
Country of publication
Switzerland
Publication subject
e-ISSN
20794991
Source type
Scholarly Journal
Language of publication
English
Document type
Journal Article
Publication history
 
 
Online publication date
2025-03-31
Milestone dates
2025-03-05 (Received); 2025-03-28 (Accepted)
Publication history
 
 
   First posting date
31 Mar 2025
ProQuest document ID
3188791014
Document URL
https://www.proquest.com/scholarly-journals/advancements-bio-nanotechnology-green-synthesis/docview/3188791014/se-2?accountid=208611
Copyright
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2025-04-11
Database
ProQuest One Academic