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Abstract

Background

Nursing pharmacology, essential for patient safety, benefits from innovative teaching methods that enhance student engagement and understanding. This study evaluates the effects of integrating pop culture and artificial intelligence (AI) into nursing pharmacology case studies, aiming to improve learning outcomes.

Method

A total of 80 AI-assisted, pop culture-infused case studies that illustrated pharmacological principles were developed using diverse media narratives. Student performance on related exam questions was compared using a paired t test.

Results

Scores for pop culture-based questions (M = 0.91 [SD = 0.065]) improved significantly compared with traditional questions (M = 0.84 [SD = 0.087]), with a large effect size (Cohen's d = 1.01, p < .001), indicating enhanced engagement and retention.

Conclusion

Incorporating pop culture and AI into pharmacology education significantly enhanced student engagement and understanding, suggesting a promising approach to making learning more accessible, enjoyable, and relevant. [J Nurs Educ. 2025;64(X):XXX–XXX.]

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