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Respiratory Syncytial Virus (RSV) causes over 50,000 hospitalizations annually among children under five years of age, leading to long-term consequences, such as asthma. Monoclonal antibodies (mAb) have been recommended for prevention, but their limitations have prompted the search for alternative preventive measures. The recent Food and Drug Administration (FDA) approval of a maternal RSV vaccine with 80% efficacy in protecting infants up to 90 days post-birth marks a significant advancement. Our narrative review investigates the differences in RSV immunization in pregnant mothers versus infants and children, with the goal of identifying factors that influence parental decisions. This study provides insights for optimising preventive strategies, and the results highlight the importance of maternal vaccination in combating RSV in children.
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; Laiba, Shamim 2
; Ibrahim, Ahmed 3
; Humayun Muhammad Abdullah 4
; Khan, Muhammad Hamza 5
; Anum, Akbar 6
; Jindal Sanmit 7
; Shahzaib, Ahmed 8
; Shrestha Jamuna 9
; Nveed, Muhammad Abdullah 1
1 Department of Internal Medicine, Dow Medical College , Karachi , Pakistan
2 Department of Internal Medicine, Sindh Medical College , Karachi , Pakistan
3 Department of Internal Medicine , Faculty of Medicine, Alexandria University , Alexandria , Egypt
4 Department of Pediatrics, Shalamar Institute of Health Sciences , Lahore , Pakistan
5 Department of Internal Medicine, Karachi Medical and Dental College , Karachi , Pakistan
6 Department of Pediatrics , University of Nebraska Medical Center , Omaha , Nebraska , USA
7 Department of Department of Population Health and Leadership , University of New Haven , Connecticut , USA
8 Department of Internal Medicine, Fatima Memorial Hospital College of Medicine and Dentistry , Lahore , Pakistan
9 Department of Pediatrics, Manipal College of Medical Sciences , Pokhara , Nepal