Content area

Abstract

Biofilms are structured microbial communities that pose significant challenges to food safety and quality within the food-processing industry. Their formation on equipment and surfaces enables persistent contamination, microbial resistance, and recurring outbreaks of foodborne illness. This review provides a comprehensive synthesis of current knowledge on biofilm formation mechanisms, genetic regulation, and the unique behavior of multi-species biofilms. The review evaluates modern detection and monitoring technologies, including PCR, biosensors, and advanced microscopy, and compares their effectiveness in industrial contexts. Real-world outbreak data and a global economic impact analysis underscore the urgency for more effective regulatory frameworks and sanitation innovations. The findings highlight the critical need for integrated, proactive biofilm management approaches to safeguard food safety, reduce public health risks, and minimize economic losses across global food sectors.

Details

1009240
Title
Persistent Threats: A Comprehensive Review of Biofilm Formation, Control, and Economic Implications in Food Processing Environments
Author
Ban-Cucerzan Alexandra 1   VIAFID ORCID Logo  ; Imre Kálmán 1   VIAFID ORCID Logo  ; Morar Adriana 1   VIAFID ORCID Logo  ; Marcu Adela 2   VIAFID ORCID Logo  ; Hotea Ionela 3   VIAFID ORCID Logo  ; Sebastian-Alexandru, Popa 1   VIAFID ORCID Logo  ; Răzvan-Tudor, Pătrînjan 1   VIAFID ORCID Logo  ; Iulia-Maria, Bucur 3   VIAFID ORCID Logo  ; Gașpar Cristina 3 ; Ana-Maria, Plotuna 3 ; Sergiu-Constantin, Ban 4 

 Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” from Timișoara, 300645 Timișoara, Romania; [email protected] (K.I.); [email protected] (A.M.); [email protected] (I.H.); [email protected] (R.-T.P.); [email protected] (I.-M.B.); [email protected] (C.G.); [email protected] (A.-M.P.), Research Institute for Biosecurity and Bioengineering, University of Life Sciences “King Mihai I” from Timișoara, 300645 Timișoara, Romania 
 Faculty of Biotechnology of Animal Resources, University of Life Sciences “King Mihai I” from Timișoara, 300645 Timișoara, Romania; [email protected] 
 Faculty of Veterinary Medicine, University of Life Sciences “King Mihai I” from Timișoara, 300645 Timișoara, Romania; [email protected] (K.I.); [email protected] (A.M.); [email protected] (I.H.); [email protected] (R.-T.P.); [email protected] (I.-M.B.); [email protected] (C.G.); [email protected] (A.-M.P.) 
 Independent Researcher, 300668 Timișoara, Romania; [email protected] 
Publication title
Volume
13
Issue
8
First page
1805
Number of pages
30
Publication year
2025
Publication date
2025
Publisher
MDPI AG
Place of publication
Basel
Country of publication
Switzerland
Publication subject
e-ISSN
20762607
Source type
Scholarly Journal
Language of publication
English
Document type
Journal Article
Publication history
 
 
Online publication date
2025-08-01
Milestone dates
2025-06-29 (Received); 2025-07-31 (Accepted)
Publication history
 
 
   First posting date
01 Aug 2025
ProQuest document ID
3244047587
Document URL
https://www.proquest.com/scholarly-journals/persistent-threats-comprehensive-review-biofilm/docview/3244047587/se-2?accountid=208611
Copyright
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2025-09-02
Database
ProQuest One Academic