Editorial: Advances in tick-borne diseases

Abstract

The research paper concluded that high-dose glucocorticoid (GC) therapy should be used cautiously as relatively high doses and early GC therapy increase mortality in SFTS patients, while low-dose GC treatment in patients with severe symptoms and low aspartate aminotransferase levels improved survival. In this study, authors proposed MEV designed for seven immunodominant epitopes from four outer membrane proteins (including two hypothetical proteins, an OmpA family protein, and PD40), which each having properties including increased antigenicity, solubility, thermostability and half-life. Studies demonstrated that, despite losing culturability, VBNC cells remained viable and retained intact cellular structures, as evidenced by transmission electron microscopy. [...]the editorial concludes with the study by Duan et al., who investigated tick-borne bacteria and their associated infections in Arxan, Inner Mongolia, China, by analyzing 282 Ixodes persulcatus, 13 Dermacentor silvarum ticks, and 245 human blood samples.