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Abstract

Sodium alginate, a natural anionic polysaccharide, exhibits broad potential applications in food, biomedicine, and environmental engineering due to its favorable biocompatibility, degradability, and functional tunability. This review systematically summarizes its chemical structure, physicochemical characteristics, sources, and extraction methods. It also focused on modification strategies, including chemical approaches (e.g., esterification, oxidation, sulfation, graft copolymerization), physical methods (composite modification, irradiation cross-linking, ultrasound treatment), and biological (e.g., enzyme regulation), and elucidated their underlying mechanisms. In the context of food science, special emphasis is placed on food-compatible chemistries and mild modification routes (such as phenolic crosslinking, enzyme-assisted coupling, and other green reactions) that enable the development of edible films, coatings, and functional carriers, while distinguishing these from non-food-oriented chemical strategies. The review further highlights novel applications of modified sodium alginate in areas including food packaging, functional delivery systems, drug release, tissue engineering, and environmental remediation (heavy metal and dye removal). Overall, this work provides a comprehensive perspective linking modification pathways to food-relevant applications and clarifies how chemical tailoring of alginate contributes to the design of safe, sustainable, and high-performance bio-based materials.

Details

1009240
Company / organization
Title
Sodium Alginate Modifications: A Critical Review of Current Strategies and Emerging Applications
Author
Wang, Wenning 1 ; Huang, Yuanyuan 1 ; Pan, Yun 1 ; Dabbour Mokhtar 2   VIAFID ORCID Logo  ; Dai Chunhua 3 ; Zhou, Man 3   VIAFID ORCID Logo  ; He Ronghai 3   VIAFID ORCID Logo 

 School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; [email protected] (W.W.); [email protected] (Y.H.); [email protected] (Y.P.); [email protected] (M.Z.); [email protected] (R.H.) 
 Department of Agricultural and Biosystems Engineering, Faculty of Agriculture, Benha University, Moshtohor, Qaluobia P.O. Box 13736, Egypt; [email protected] 
 School of Food and Biological Engineering, Jiangsu University, Zhenjiang 212013, China; [email protected] (W.W.); [email protected] (Y.H.); [email protected] (Y.P.); [email protected] (M.Z.); [email protected] (R.H.), Institute of Food Physical Processing, Jiangsu University, Zhenjiang 212013, China 
Publication title
Foods; Basel
Volume
14
Issue
22
First page
3931
Number of pages
42
Publication year
2025
Publication date
2025
Publisher
MDPI AG
Place of publication
Basel
Country of publication
Switzerland
Publication subject
e-ISSN
23048158
Source type
Scholarly Journal
Language of publication
English
Document type
Journal Article
Publication history
 
 
Online publication date
2025-11-17
Milestone dates
2025-10-03 (Received); 2025-11-14 (Accepted)
Publication history
 
 
   First posting date
17 Nov 2025
ProQuest document ID
3275512594
Document URL
https://www.proquest.com/scholarly-journals/sodium-alginate-modifications-critical-review/docview/3275512594/se-2?accountid=208611
Copyright
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2025-12-03
Database
ProQuest One Academic