Content area
Objectives
To assess human papillomavirus (HPV) vaccine awareness and uptake among caregivers in rural Indigenous communities in Guatemala and to identify sociodemographic predictors of vaccine unawareness and non-uptake.
Methods
This cross-sectional survey was conducted across 12 rural Indigenous communities in Guatemala’s Central Highlands. Using a community-engaged research approach, trained multilingual health workers administered surveys in Spanish, Kaqchikel or K’iche’. Eligible participants were adults who served as primary caregivers to children. The survey assessed HPV vaccine awareness, vaccine attitudes and uptake among those with daughters aged 8 or older. Logistic regression was used to examine predictors of vaccine unawareness and bivariate analysis explored differences in vaccine uptake.
Results
Among 602 participants (92.5% identified as Indigenous), 95% expressed willingness to vaccinate a child against cervical cancer, yet only 56% had heard of the HPV vaccine. Of the 175 participants with eligible daughters, only 33.7% reported vaccination. Indigenous identity, older age and illiteracy were significantly associated with HPV vaccine unawareness. Speaking an Indigenous language at home was associated with greater awareness. Departmental differences were significant: participants from Sololá were more likely to be unaware of the vaccine, while those from Sacatepéquez had higher awareness and uptake. Community partners noted that access to information, geographic connectivity and social desirability may influence both awareness and response accuracy.
Conclusions
Despite strong willingness to vaccinate, significant knowledge gaps persist among Indigenous caregivers. Tailored, community-informed education strategies—delivered through trusted channels and adapted linguistically and culturally—are urgently needed to increase awareness and uptake of the HPV vaccine in underserved Guatemalan communities.
Details
Vaccines;
Womens health;
Health education;
Self report;
Community health care;
Public health;
Cervical cancer;
Data collection;
Multilingualism;
Children & youth;
Disease prevention;
Medical screening;
Caregivers;
Human papillomavirus;
Qualitative research;
Immunization;
Literacy;
Quality of life;
Mental health;
Aging;
Sport science
1 Institute for Global Health Sciences , University of California San Francisco , San Francisco , California , USA
2 Chimaltenango Department , Maya Health Alliance Wuqu’ Kawoq , Tecpán Guatemala , Guatemala
3 Stanford Center for Health Education , Stanford University , Stanford , California , USA
4 Pediatrics , Stanford University , Stanford , California , USA
5 Maya Health Alliance Wuqu’ Kawoq , Tecpan , Guatemala
6 Institute for Global Health Sciences , University of California San Francisco , San Francisco , California , USA, Epidemiology and Biostatistics , University of California San Francisco , San Francisco , California , USA