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Abstract

This prospective, single-arm study investigates the effects of preservative-free artificial tears on ocular symptoms, visual task performance, and tear film stability in visual display terminal (VDT) users. Thirty VDT users with digital eye strain and dryness symptoms were prescribed preservative-free artificial tears four times daily for one month. Ocular Surface Disease Index (OSDI) and Computer–Vision Symptom Scale (CVSS17) questionnaires were collected at four visits (screening, initial, one week and one month). Blink rate and eye fixations during six simple computer tasks and out-loud reading speed were determined before and after computer use. Noninvasive tear film break-up time (NIBUT) and tear meniscus height (TMH) were also recorded. VDT users’ symptoms [CVSS17 (35.70 ± 3.72 to 27.27 ± 4.43; P < 0.01); OSDI (19.99 ± 3.20 to 10.52 ± 6.04; P < 0.01)] improved after artificial tear use at final visit. Out-loud reading speed did not significantly change, although a slight improvement in the normalized value was observed after computer use between the initial (0.99 ± 0.13) and final (1.02 ± 0.15; P < 0.01) visits. No significant differences between visits were found in the blink rate, eye fixations, NIBUT or TMH. Preservative-free artificial tears effectively reduce subjective symptoms in VDT users, although this relief does not translate into measurable improvements in visual task performance or tear film metrics.

Details

1009240
Title
Effects of artificial tears on ocular surface symptoms and visual task performance in digital device users
Author
Ortiz-Toquero, Sara 1 ; Sanchez, Irene 1 ; Martin, Raul 1 

 Optometry Research Group, IOBA Eye Institute, University of Valladolid, 47011, Valladolid, Spain (ROR: https://ror.org/01fvbaw18) (GRID: grid.5239.d) (ISNI: 0000 0001 2286 5329); Departamento de Física Teórica, Atómica y Óptica, Universidad de Valladolid, Paseo de Belén, 7 - Campus Miguel Delibes, 47011, Valladolid, Spain (ROR: https://ror.org/01fvbaw18) (GRID: grid.5239.d) (ISNI: 0000 0001 2286 5329) 
Volume
16
Issue
1
Pages
653
Number of pages
11
Publication year
2026
Publication date
2026
Section
Article
Publisher
Nature Publishing Group
Place of publication
London
Country of publication
United States
Publication subject
e-ISSN
20452322
Source type
Scholarly Journal
Language of publication
English
Document type
Journal Article
Publication history
 
 
Online publication date
2025-12-26
Milestone dates
2025-09-29 (Registration); 2025-05-23 (Received); 2025-09-29 (Accepted); 2026-01-07 (Version-Of-Record)
Publication history
 
 
   First posting date
26 Dec 2025
ProQuest document ID
3291113810
Document URL
https://www.proquest.com/scholarly-journals/effects-artificial-tears-on-ocular-surface/docview/3291113810/se-2?accountid=208611
Copyright
© The Author(s) 2026. This work is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the "License"). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Last updated
2026-01-08
Database
2 databases
  • Coronavirus Research Database
  • ProQuest One Academic