Abstract

细胞自噬是机体细胞组织的自我防御和自我修复的过程,在调节机体的免疫炎症反应和维持肝细胞内环境平衡中发挥重要作用。从自噬调节免疫炎症反应、自噬调节免疫信号传导和防止过度激活的先天免疫反应方面,总结自噬在自身免疫性肝炎(AIH)发生发展中的作用机制。认为从细胞自噬角度可能揭示AIH的作用机制,为AIH的研究提供新思路和新方法。

Alternate abstract:

Autophagy is a process of self-defense and self-repair of cells and tissues and plays an important role in regulating the body's immune inflammatory response and maintaining the homeostasis of liver cells. This article summarizes the mechanism of autophagy in the development and progression of autoimmune hepatitis (AIH) from the aspects of the role of autophagy in regulating immune inflammatory response, regulating immune signal transduction, and preventing overactivated innate immune response. It is believed that autophagy may reveal the mechanism of AIH and provide new ideas and methods for the research on AIH.

Details

Title
细胞自噬在自身免疫性肝炎发生发展中的作用机制
Author
杨培伟; 刘光伟; 赵文霞
Pages
2689-2691
Section
Reviews
Publication year
2021
Publication date
2021
Publisher
Journal of Clinical Hepatology
ISSN
10015256
e-ISSN
20973497
Source type
Scholarly Journal
Language of publication
Chinese
ProQuest document ID
3239708568
Copyright
© 2021. This work is published under https://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.