Abstract
Available toxicological studies on vitamin D3 also revealed sex specific variation in its oral LD50, as this value was found to be 42 mg/kg for males and 619 mg/kg for female rats (Bennett 2002), but no reports regarding LD50 value of cholecalciferol against house rats are available in literature. [...] the present study concluded that value of LD50 of orally administered cholecalciferol (vitamin D3) is sex specific and males are more susceptible to its toxicity than the female house rats.
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