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Copyright Termedia Publishing House 2011

Abstract

Introduction : We investigated the association between bone mineral density (BMD) detected by dual-energy X-ray absorptiometric (DXA) method and blood pressure (BP) in a large sample of postmenopausal women.

Material and methods : The current study was based on a retrospective analysis of 586 postmenopausal women with a mean age of 60.8 ±8.8 years, who were screened for osteopenia or osteoporosis by DXA. Patients with hypertension (HT, n = 306) were compared with normotensive (NT, n = 290) individuals. Bone mineral density results for the femur neck and spine were classified into 3 groups according to World Health Organization criteria: normal (T score > -1.0 SD), osteopenia (T score -1.0 to -2.5 SD) and osteoporosis (T score < -2.5 SD). Patients with osteopenia or osteoporosis (T score < -1.0 SD) were grouped as having low bone mass (LBM).

Results : There were no significant differences in femur T score, femur BMD, femur Z score, spinal T score, spinal BMD and spinal Z score between hypertensive and normotensive groups. The group of patients with low bone mass calculated from femur T scores had higher age, systolic BP, duration of hypertension and duration of menopause, but lower BMI. Similarly, patients with low spine BMD had higher age and duration of menopause, but lower BMI. Linear regression analysis showed a significant correlation between systolic BP and femur BMD and T score values. Furthermore, logistic regression analysis revealed that hypertension is an independent predictor of spinal osteopenia and osteoporosis.

Conclusions : The presence of hypertension is an independent predictor of spinal low bone density in Turkish women after menopause.

Details

Title
Relationship between blood pressure levels and bone mineral density in postmenopausal Turkish women
Author
Yazici, Selma; Yazici, Mehmet; Korkmaz, Ugur; Erkan, Melih Engin; Ali Erdem Baki; Ismail Erden; Ozhan, Hakan; Ataoglu, Safinaz
First page
264
Section
Clinical research
Publication year
2011
Publication date
2011
Publisher
Termedia Publishing House
ISSN
17341922
e-ISSN
18969151
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
919663901
Copyright
Copyright Termedia Publishing House 2011