Abstract

A 70-year-old man was admitted to our clinic with complaints of fever, jaundice, dyspnea, and generalized rash after 3 months of allopurinol treatment for gout. On physical examination, he was found to have fever (38.5C), jaundice, and generalized maculopapular rash. Leukocytosis, eosinophilia, elevation of liver enzymes, and hyperbilirubinemia were detected in his blood analysis. Skin biopsy was consistent with drug-induced hypersensitivity. He was diagnosed as Drug Rash with Eosinophilia and Systemic Symptoms (DRESS). Allopurinol treatment was stopped and steroid treatment was launched. At day 24 of admission, the patient died because of multiple organ failure.[PUBLICATION ABSTRACT]

Details

Title
Allopurinol-induced DRESS syndrome
Author
Yaylaci, Selcuk; Demir, Mustafa; Temiz, Tayfun; Tamer, Ali; Uslan, Mustafa
Pages
412-414
Publication year
2012
Publication date
May/Jun 2012
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
02537613
e-ISSN
19983751
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1021159236
Copyright
Copyright Medknow Publications & Media Pvt Ltd May/Jun 2012