Abstract

Doc number: 83

Abstract

Background: To identify risk factors for suicide using data from a large, 3-year, multinational follow-up study of schizophrenia (SOHO study).

Methods: Baseline characteristics of 8,871 adult patients with schizophrenia were included in a logistic regression post-hoc analysis comparing patients who attempted and/or committed suicide during the study with those who did not.

Results: 384 (4.3%) patients attempted or committed suicide. Completed suicides were 27 (0.3%). The significant risk factors for suicide behaviors were previous suicidality, depressive symptoms, prolactin-related adverse events, male gender and history of hospitalization for schizophrenia.

Conclusions: In view of the observational design of the study and the post-hoc nature of the analysis, the identified risk factors should be confirmed by ad-hoc specifically designed studies.

Details

Title
Risk factors for suicide behaviors in the observational schizophrenia outpatient health outcomes (SOHO) study
Author
Brugnoli, Roberto; Novick, Diego; Haro, Josep Maria; Rossi, Andrea; Bortolomasi, Marco; Frediani, Sonia; Borgherini, Giuseppe
Pages
83
Publication year
2012
Publication date
2012
Publisher
BioMed Central
e-ISSN
1471244X
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/1471-244X-12-83
ProQuest document ID
1031554160
Copyright
© 2012 Brugnoli et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.