Abstract

Doc number: 372

Abstract: The World Health Organization (WHO) convened a malaria vaccines committee (MALVAC) scientific forum from 20 to 21 February 2012 in Geneva, Switzerland, to review the global malaria vaccine portfolio, to gain consensus on approaches to accelerate second-generation malaria vaccine development, and to discuss the need to update the vision and strategic goal of the Malaria Vaccine Technology Roadmap. This article summarizes the forum, which included reviews of leading Plasmodium falciparum vaccine candidates for pre-erythrocytic vaccines, blood-stage vaccines, and transmission-blocking vaccines. Other major topics included vaccine candidates against Plasmodium vivax , clinical trial site capacity development in Africa, trial design considerations for a second-generation malaria vaccine, adjuvant selection, and regulatory oversight functions including vaccine licensure.

Details

Title
MALVAC 2012 scientific forum: accelerating development of second-generation malaria vaccines
Author
Vannice, Kirsten S; Brown, Graham V; Akanmori, Bartholomew D; Moorthy, Vasee S
Pages
372
Publication year
2012
Publication date
2012
Publisher
BioMed Central
e-ISSN
14752875
Source type
Scholarly Journal
Language of publication
English
DOI
https://doi.org/10.1186/1475-2875-11-372
ProQuest document ID
1224747040
Copyright
© 2012 Vannice et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.