Abstract

Doc number: 102

Abstract: The clockwise rotation of cilia in the developing mammalian embryo drives a leftward flow of liquid; this genetically regulated biophysical force specifies left-right asymmetry of the mammalian body. How leftward flow is interpreted and information propagated to other tissues is the subject of debate. Four recent papers have shed fresh light on the possible mechanisms.

Details

Title
Cilia, calcium and the basis of left-right asymmetry
Author
Norris, Dominic P
Pages
102
Publication year
2012
Publication date
2012
Publisher
BioMed Central
e-ISSN
17417007
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1240891459
Copyright
© 2012 Norris; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.