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Copyright Korean Society of Pathologists, Korean Society for Cytopathology Dec 2012

Abstract

Mucinous cystadenocarcinoma (MCA) in the breast is a rare neoplasm. There have been 13 cases of primary breast MCA reported. The MCA presents as a large, partially cystic mass in postmenopausal woman with a good prognosis. The microscopic findings resemble those of ovarian, pancreatic, or appendiceal MCA. The aspiration findings showed mucin-containing cell clusters in the background of mucin and necrotic material. The cell clusters had intracytoplasmic mucin displacing atypical nuclei to the periphery. Histologically, the tumor revealed an abundant mucin pool with small floating clusters of mucin-containing tumor cells. There were also small cysts lined by a single layer of tall columnar mucinous cells, resembling those of the uterine endocervix. The cancer cells were positive for mucin (MUC) 5 and negative for MUC2 and MUC6. This mucin profile is different from ordinary mucinous carcinoma and may be a unique characteristic of breast MCA. [PUBLICATION ABSTRACT]

Details

Title
Primary Mucinous Cystadenocarcinoma of the Breast: Cytologic Finding and Expression of MUC5 Are Different from Mucinous Carcinoma
Author
Kim, Sung Eun; Park, Ji Hye; Hong, SoonWon; Koo, Ja Seung; Jeong, Joon; Jung, Woo-Hee
Pages
611-616
Section
CASE REPORT
Publication year
2012
Publication date
Dec 2012
Publisher
Korean Society of Pathologists, Korean Society for Cytopathology
ISSN
17381843
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1285166500
Copyright
Copyright Korean Society of Pathologists, Korean Society for Cytopathology Dec 2012