Abstract

Diffuse large B-cell lymphoma (DLBCL) is a subtype of non-Hodgkin's lymphoma (NHL) making up about approximately 30% of all NHL. Its occurrence in the mandible is very rare. Histopathologically, five variants of DLBCL have been recognized among which centroblastic variant is the one with better prognosis. We report a case of a 55 year-old patient who presented with a painless swelling in the lower right body of the mandible since 4 months. Incisional biopsy revealed NHL like features, confirmed by immunohistochemistry using CD45, CD20, and CD3 markers to be a DLBCL of centroblastic variant. Patient was treated with chemotherapy following which the lesion regressed completely with no further recurrences. Precise histological diagnosis is crucial for the clinical management and ultimately for the survival of the patient. [PUBLICATION ABSTRACT]

Details

Title
Centroblastic variant of diffuse large B-cell lymphoma: Case report and review of literature
Author
Nayak, Preethi; Desai, Dinkar; Pandit, Siddharth; Rai, Nisha
Pages
261-265
Publication year
2013
Publication date
May-Aug 2013
Publisher
Medknow Publications & Media Pvt. Ltd.
ISSN
0973029X
e-ISSN
1998393X
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1444544466
Copyright
Copyright Medknow Publications & Media Pvt Ltd May-Aug 2013