Abstract

New arylsulfonyl proton pump inhibitor (PPI) prodrug forms were synthesized. These prodrugs provided longer residence time of an effective PPI plasma concentration, resulting in better gastric acid inhibition.

Details

Title
1-Arylsulfonyl-2-(Pyridylmethylsulfinyl) Benzimidazoles as New Proton Pump Inhibitor Prodrugs
Author
Shin, Jai Moo; Sachs, George; Cho, Young-moon; Garst, Michael
Pages
5247-5280
Publication year
2009
Publication date
2009
Publisher
MDPI AG
e-ISSN
14203049
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1531504946
Copyright
Copyright MDPI AG 2009