Abstract

A fast and non-destructive voltammetric method to detect cocaine in confiscated samples based on carbon paste electrode modified with methoxy-substituted N,N'-ethylene-bis(salcylideneiminato)uranyl(VI)complexes, [UO2(X-MeOSalen)(H2O)]*H2O, where X corresponds to the positions 3, 4 or 5 of the methoxy group on the aromatic ring, is described. The electrochemical behavior of the modified electrode and the electrochemical detection of cocaine were investigated using cyclic voltammetry. Using 0.1 mol*L-1 KCl as supporting-electrolyte, a concentration-dependent, well-defined peak current for cocaine at 0.62 V, with an amperometric sensitivity of 6.25 × 104 μA*mol*L-1 for cocaine concentrations ranging between 1.0 × 10-7 and 1.3 × 10-6 mol*L-1 was obtained. Chemical interference studies using lidocaine and procaine were performed. The position of the methoxy group affects the results, with the 3-methoxy derivative being the most sensitive.

Details

Title
Voltammetric Determination of Cocaine in Confiscated Samples Using a Carbon Paste Electrode Modified with Different [UO2(X-MeOsalen)(H2O)]*H2O Complexes
Author
Oliveira, Laura Siqueira de; Santos, Ana Paula dos; Balbino, Marco Antonio; de, Matheus Manoel Teles; Andrade, Jose Fernando de; Dockal, Edward Ralph; Tristão, Heloísa Maria; Oliveira, Marcelo Firmino de
Pages
7668-7679
Publication year
2013
Publication date
2013
Publisher
MDPI AG
e-ISSN
14248220
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1539267071
Copyright
Copyright MDPI AG 2013