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Copyright Korean Society of Pathologists, Korean Society for Cytopathology Dec 2014

Abstract

Polymerase chain reaction analysis for TCRy gene rearrangement revealed monoclonality (Fig. 1). Because the initial diagnosis was PTCL-NOS, Ann Arbor stage IE, the patient was treated with chemotherapy including cyclophosphamide, doxorubicin, vincristine, and prednisone for six cycles during 4 months. In immunohistochemistry, tumor cells are usually CD4-CD8+CD56+, and less frequently CD4-CD8-CD56+. Because indolent T-cell LPD shows superficial infiltration of small, mature appearing lymphoid cells with a low Ki-67 labeling index of less than 10%, Ki-67 staining is important for excluding aggressive T-cell lymphoma such as PTCL-NOS or EATL.6 Histological and immunohistochemical findings of present case are very similar to those of lymphomatoid gastropathy.

Details

Title
Indolent CD56-Positive Clonal T-Cell Lymphoproliferative Disease of the Stomach Mimicking Lymphomatoid Gastropathy
Author
Hong, Mineui; Kim, Won Seog; Ko, Young Hyeh
Pages
430-433
Section
BRIEF CASE REPORT
Publication year
2014
Publication date
Dec 2014
Publisher
Korean Society of Pathologists, Korean Society for Cytopathology
ISSN
17381843
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1644296928
Copyright
Copyright Korean Society of Pathologists, Korean Society for Cytopathology Dec 2014