Abstract

Electroporation involves applying electric field pulses to cells, leading to the alteration or destruction of cell membranes. Irreversible electroporation (IRE) creates permanent defects in cell membranes and induces cell death. By directly targeting IRE to tumors, percutaneous nonthermal ablation is possible. The history of IRE, evolution of concepts, theory, biological applications, and clinical data regarding its safety and efficacy are discussed.

Details

Title
Irreversible electroporation: evolution of a laboratory technique in interventional oncology
Author
Deipolyi, Amy; Golberg, Alexander; Yarmush, Martin L; Arellano, Ronald S; Oklu, Rahmi
Pages
147-154
Section
Interventional Radiology - Original Article
Publication year
2014
Publication date
Mar 2014
Publisher
Aves Yayincilik Ltd. STI.
ISSN
13053825
e-ISSN
13053612
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1676093470
Copyright
Copyright Aves Yayincilik Ltd. STI. Mar 2014