Dexamethasone action on caudal fin regeneration of carp Cyprinus carpio (Linnaeus, 1758)

Abstract

The aim of the present study was to investigate the effect of dexamethasone during the regeneration process in the caudal fin of specimens of carp (Cyprinus carpio). For such, two glass aquaria were used -- one for a group of fish treated with dexamethasone (Henrifarma) in a 20 mg/L concentration and the other for the control group. The caudal fins were amputated transversally and fish remained in their respective aquaria until regeneration occurred. Samples of regenerating fins were collected on days 1, 2, 4, 6, 8 and 10 after amputation. The fins in the group treated with dexamethasone were significantly smaller in comparison to the control group at every evaluation time. The results show that the caudal fin is a good model for histological studies on regeneration and the action of drug toxicity, but it's also of great importance the interaction with further studies for a better knowledge and understanding of all the changes in all the phases.