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Abstract
Background: Prostate cancer is one of the most common causes of cancer mortality among men in the USA and several genetic variants have been found to be associated with Prostate Cancer aggressiveness. Identifying their association with Prostate Cancer survival can help in clinical decision making and reduce unnecessary interventions.
Objective: The objective of the study is to develop an association between SNPs and Gene Expression and Prostate Cancer Survival.
Result: SNP rs2702185 was found to increase the risk of death by 170%. SNP rs73055188 increased the risk of Biochemical Recurrence and Death by 43%.
Conclusion: SNPs were found in African American population which replicated the results observed in European population. SNP rs2702185 and rs73055188 were found to be associated with Biochemical Recurrence and Death in European population.
