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Copyright © 2013 Yu-xia Ma et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/

Abstract

Objective. To explore the efficacy of Herb-partitioned moxibustion in treating IBS-D patients. Method. 210 IBS-D patients were randomly assigned on a 3 : 3 : 2 basis to group HM, group FM, or group PB for 4-week treatment. The change of GSRS total score at weeks 4 and 8, the changes of GSRS specific scores, and adverse events were evaluated. Results. Patients in group HM and group FM had lower GSRS total score at week 4 ( 1.98 ± 0.303 , 2.93 ± 0.302 versus 3.73 ± 0.449 ) and at week 8 ( 2.75 ± 0.306 , 3.56 ± 0.329 versus 4.39 ± 2.48 ) as compared with patients’ score in group PB. However, there was no significant difference of GSRS total score between group HM and group FM. The effect of HM was significantly greater than that of orally taking PB in ameliorating the symptoms of rugitus (0.38 versus 0.59, P < 0.05 ), abdominal pain (0.28 versus 0.57, P < 0.01 ), abdominal distension (0.4 versus 0.7, P < 0.01 ), and increased passage of stools (0.06 versus 0.25, P < 0.01 ) at the end of treatment period. In the follow-up period, patients’ therapeutic effect in group HM remained greater than that in group FM (in abdominal pain, abdominal distension, and increased passage of stools) and that in group PB (in loose stools). Conclusions. HM appears to be a promising, efficacious, and well-tolerated treatment for patients with IBS-D.

Details

Title
Randomized Clinical Trial: The Clinical Effects of Herb-Partitioned Moxibustion in Patients with Diarrhoea-Predominant Irritable Bowel Syndrome
Author
Yu-xia, Ma 1 ; Liu, Xiao 1 ; Liu, Cun-zhi 2 ; Lin-peng, Wang 2 ; Guo, Gang 3 ; Dong-qing Du 1 ; Zhi-lei, Wang 1 ; Ma, Hong 1 ; Qi, Ping 1 ; Zhao-feng, Li 1 ; Yan-ping, Guo 4 ; Hua-qiang, Yi 1 ; Shu-zhong, Gao 1 

 Shandong University of Traditional Chinese Medicine, Shandong, Jinan 250014, China 
 Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medicine University, Beijing 10010, China 
 Qilu Hospital Affiliated to Shandong University, Shandong, Jinan 250012, China 
 Qianfoshan Hospital Affiliated to Shandong University, Shandong, Jinan 250014, China 
Editor
Pinar Atukeren
Publication year
2013
Publication date
2013
Publisher
John Wiley & Sons, Inc.
ISSN
1741427X
e-ISSN
17414288
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1710742250
Copyright
Copyright © 2013 Yu-xia Ma et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0/