Abstract

An efficient multi-component reaction to synthesize multi-substituted 1,3-oxazolidine compounds of high optical purity was described. All the products were well-characterized and the absolute configuration of one chiral center was determined. The plausible mechanism was proposed and a kinetic resolution of epoxides process was confirmed.

Details

Title
Asymmetric Synthesis of 1,3-Oxazolidine Derivatives with Multi-Component Reaction and Research of Kinetic Resolution
Author
Hong, Xiao-Wei; Zhou, Yu-Qiang; Bai, Cui-Bing; Wang, Nai-Xing; Xing, Yalan; Zhang, Wei; Wang, Yan-Jing; Lan, Xing-Wang; Xie, Yu; Li, Yi-He
Pages
17208-17220
Publication year
2015
Publication date
2015
Publisher
MDPI AG
e-ISSN
14203049
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1721945678
Copyright
Copyright MDPI AG 2015