Abstract
Background Wnt signaling pathways are highly conserved signal transduction pathways that have widespread functions during development in all metazoans including essential roles in cell fate specification, cell proliferation, and embryonic axis formation [1-3]. High levels of nuclear beta-catenin promote the formation of transcriptional activators, elicit new gene expression, and lead to subsequent specification of cell fates [1, 7-9]. Bf, Brachiostoma floridae; Cg, Crassostrea gigas; Ct, Capitella teleta; Dr, Danio rerio; Gg, Gallus gallus; Hs, Homo sapiens; Nv, Nematostella vectensis; Pd, Platynereis dumerilii; Sk, Saccoglossus kowalevskii; Sp, Strongylocentrotus purpuratus; Xl, Xenopus laevis. 13227_2015_32_MOESM2_ESM.pdf Additional file 3: Bf, Brachiostoma floridae; Cg, Crassostrea gigas; Ct, Capitella teleta; Dr, Danio rerio; Gg, Gallus gallus; Hs, Homo sapiens; Nv, Nematostella vectensis; Pd, Platynereis dumerilii; Sk, Saccoglossus kowalevskii; Sp, Strongylocentrotus purpuratus; Xl, Xenopus laevis. 13227_2015_32_MOESM4_ESM.pdf Additional file 4:
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