Perfiles serológicos de hepatitis B en donantes de sangre con anti-HBc reactivos

Abstract

Objective To assess the serological profiles for HBV in blood donors that were anti-HBc reactive and non-reactive to HBsAg in four Colombian cities.

Materials and Methods A prospective cross-sectional study was conducted over 17 months, applying a complete serological profile for HBV in samples from blood donors that were anti-HBc reactive and non-reactive to HBsAg. Results were analyzed employing descriptive statistics using Microsoft Excel and Epiinfo V. 3.5.1. Results Of donors reactive to anti-HBc, 75.0 % showed some additional infection marker for HBV. 1.3 % of blood donors had serological markers for chronic hepatitis B infection and one case had reactivity only for hepatitis B surface antigen (HBsAg). 6.1 % of donors showed a vaccination serological profile with reactivity only to anti-HBsAg antibodies.

Conclusions With this study, the importance of anti-HBc blood screening was confirmed.