Multiple systemic embolism in infective endocarditis underlying in Barlows disease

Abstract

Systemic embolism, particularly septic embolism, is a severe complication of IE. However, concurrent embolism to the brain, coronary arteries, and spleen is very rare. Because of the risk of hemorrhage or visceral rupture, anticoagulants are recommended only if an indication for anticoagulation is present [1], e.g. prosthetic valve. Also, antiplatelet therapy in IE remains controversial, with available clinical trials and animal experiments providing contradictory results. Theoretically, antiplatelet therapy has the potential to inhibit and treat thrombosis and embolism in IE. Unfortunately, the results of clinical trials are inconclusive.