Abstract

Three new2-(2-phenylethyl)chromone derivatives (1-3) and a new2-(2-phenylethenyl)chromone derivative (4), together with two known 2-(2-phenylethyl)chromone derivatives (5-6), were isolated from agarwood originating from Gyrinops salicifolia Ridl. The structures of compounds 1-4 were elucidated by comprehensive spectroscopic techniques (UV, IR, 1D and 2D-NMR) and MS analysis, as well as by comparison with the literature. Compounds 1, 2, and 5 showed moderate cytotoxicity against human tumor K562, BEL-7402, and SGC-7901 cell lines with IC50 values of 5.76 to 20.1 µM.

Details

Title
2-(2-Phenylethyl)chromone Derivatives of Agarwood Originating from Gyrinops salicifolia
Author
Shao, Hang; Mei, Wen-Li; Dong, Wen-Hua; Gai, Cui-Juan; Li, Wei; Zhu, Guo-Peng; Dai, Hao-Fu
First page
1313
Publication year
2016
Publication date
2016
Publisher
MDPI AG
e-ISSN
14203049
Source type
Scholarly Journal
Language of publication
English
ProQuest document ID
1831841166
Copyright
Copyright MDPI AG 2016