Abstract

Uric acid is a final product of purine metabolism, and its concentration in the blood serum of healthy individuals is 3-7 mg/dl. Hyperuricemia is associated with higher cardiovascular risk, and its prevalence related to nutrition profile is characteristic for highly developed societies. It can lead to the appearance of certain skin lesions. On the other hand, uric acid is an important antioxidant, which is responsible for 2/3 of the antioxidant capacity of the body. In this article, the authors present skin lesions associated with gout (tophi, "miliarial gout", gouty panniculitis) and review the data of the literature and discuss the importance of hyperuricemia in psoriasis. Dermatologists' awareness and knowledge about hyperuricemia may favor a faster diagnosis of this metabolic disorder based on skin lesions.

Details

Title
Effects of hyperuricemia on the skin
Author
Owczarczyk-Saczonek, Agnieszka; Krajewska-Wlodarczyk, Magdalena; Placek, Waldemar
Pages
40-49
Publication year
2017
Publication date
2017
Publisher
Termedia Publishing House
ISSN
00332526
e-ISSN
20849893
Source type
Scholarly Journal
Language of publication
Polish; English
ProQuest document ID
1876180936
Copyright
Copyright Termedia Publishing House 2017