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Abstract
Ultrasound examinations, high-resolution ultrasound biomicroscopy (UBM), fluorescein angiography, optical coherence tomography, computerized tomography (CT), magnetic resonance imaging (MRI), and fine-needle aspiration biopsy are technologies that may help with early tumor detection. Information on clinical symptoms, signs, results of imaging technology, drug therapy/surgical management, and pathology was collected as well. Conjunctival and ciliary congestion, corneal edema, mydriasis, and iris neovascularity occurred in some cases. Because these symptoms and clinical signs were similar to glaucoma, all these cases were misdiagnosed as primary or secondary glaucoma. {Table 1} Among them, case 1 was referred to the emergency department due to her symptoms and was diagnosed as primary acute angle-closure glaucoma in the first visit [Figure 1]a. However, on the 2 nd and 3 rd days, a rapid progression, hyphema, and obvious chemosis appeared [Figure 1]b and 1c. A large mass was discovered by B-scan ultrasound [Figure 1]d but not with UBM [Figure 1]e. At the same time, MRI prompted the possibility of choroid melanoma [Figure 1]f. The patient underwent enucleation and was diagnosed with choroid melanoma of the right eye after a pathological evaluation. What was special about case 2 was that brown nodules in the iris and many pigment depositions were found in the trabecular meshwork in the corresponding place of the anterior synechia under a slit-lamp [Figure 1]g and gonioscope [Figure 1]h. Then, a UBM [Figure 1]i was immediately conducted and found a 4.5 mm × 3.5 mm iris-ciliary body mass. [...]it is very important not to delay the diagnosis and...