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Jia-Li Liang [1; 2] and Jia-Zhen Wu [2; 3] and Yu-Hong Liu [1; 2] and Zhen-Biao Zhang [1; 2] and Qi-Duan Wu [3] and Han-Bin Chen [2; 3] and Yan-Feng Huang [1; 2] and Yao-Xing Dou [2; 3] and Jiang-Tao Zhou [1; 2] and Zi-Ren Su [1; 2; 4] and Janis Ya-Xian Zhan [1]

Academic Editor: Rajesh Singh

1, Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China, gzucm.edu.cn

2, Guangdong Provincial Key Laboratory of New Drug Development and Research of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510006, China, gzucm.edu.cn

3, The First Affiliated Hospital of Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China, gzucm.edu.cn

4, Dongguan Mathematical Engineering Academy of Chinese Medicine, Guangzhou University of Chinese Medicine, Dongguan 523808, China, gzucm.edu.cn

Received Jan 12, 2017; Revised Jun 5, 2017; Accepted Jun 13, 2017

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

1. Introduction

Acute inflammation is an initial protective response of an immunological defense system to harmful stimuli such as microbial infections, allergens, and physical injuries [1], which is characterized by redness, swelling, heat, and arteriosclerosis [2]. Pathogenesis of acute inflammation involves various signaling molecules such as COX-2, iNOS, and NF-κB [3]. Growing evidence demonstrates that acute inflammation plays an important role in maintenance of the organic integrity and is related to various diseases such as diabetes, cardiovascular dysfunction, and cancer [4]. All the time, nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed therapeutics for inflammatory diseases. However, they become increasingly controversial due to their side effects like gastric lesions [5]. Therefore, in recent decades, more and more attention has been paid to seeking alternatives with fewer side effects, and a number of natural compounds derived from traditional Chinese herbs such as curcumin and quercetin [6] have been found to have great anti-inflammatory potential.

Pogostemon cablin (Blanco) Benth. (Labiatae) is an aromatic herb native to the Philippines and has been widely cultivated in Southeast Asia [7]. As a traditional Chinese medicinal plant, P. cablin is commonly used to resolve dampness, dispel summerheat, and relieve fatigue. Patchouli oil is the...

 

 

 

 

 

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